1. withdrawal
gastrointestinal symptoms of nausea, vomiting and anorexia, accompanied by headache, giddiness, chills and insomnia, and sometimes by hypomania, panic-anxiety, and extreme motor restlessness may occur if an antidepressant (particularly MAOIs) is stopped suddenly after regular administration for 8 weeks or more. Therefore the dose should preferably be reduced gradually over about 4 weeks.
2. Cardiovascular side effects
Arrhythmias and heart block (tricyclic and relate antidepressants)
3. Central nervous system side effects
Convulsion (tricyclic and relate antidepressants)
4. Hepatic and renal effects
5. Other side effects
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