Selective Serotinin Reuptake Inhibitors (SSRIs)

This is a newer class of antidepressants. SSRIs should be used with caution in patients with epilepsy (avoid if poorly controlled, discontinue if convulsuin develop), concurrent electroconvulsive therapy (prolonged seizures reported with fluoxetin), history of mania, cardiac disease, diabetes mellitus, angle closure glaucoma, concomitant use of drugs that increase risk of bleeding, history ofbleeding disorders 9especially gastrointestinal bleeding), hepatic and renal impairment, pregnancy and breast feeding.

Common SSRIs are;

1. Citalopram
2. Escitalopram
3. Fluoxetin
4. Fluvoxamine maleate
5. Paroxetine
6. Sertraline